4-Methylthiazole-5-carboxaldehyde - 4-Methylthiazole-5-carboxaldehyde

4-Methylthiazole-5-carboxaldehyde

4-Methylthiazole-5-carboxaldehyde is a light yellow crystal. This substance is widely used in the field of pharmaceutical intermediates, for instance, as a raw material for the synthesis of ceftol ampiretin. According to T/CCIIA0004-2024 "Classification of Fine Chemical Products", Belonging to 7.4 fine chemical intermediates, 040302 contains a diheteroatom five-segment heterocyclic ring.

Chemical Formula: C₅H₅NOS

Molecular Weight: 127.164

CAS No.: 82294-70-0

Structural Type:

Appearance And Properties: Pale yellow crystals

Application: 4-Methylthiazole-5-carboxaldehyde is an important intermediate for the production of ceftol pile-up. Ceftol piloproxil is a third-generation oral cephalosporin antibiotic developed by Meiji Fruit Co., Ltd. of Japan in 1994. It is used to treat infections caused by Gram-positive and Gram-negative bacteria, especially Gram-positive bacteria of the Staphylococcus genus, including Streptococcus pneumoniae. Gram-negative bacteria such as Escherichia coli, Staphylococcus catarrhalis, Klebsiella, Proteus, Haemophilus influenzae, as well as anaerobic bacteria such as Streptococcus pneumoniae, Propionibacterium acnes, Bacteroides, etc., all demonstrated strong antibacterial power. Due to its broad antibacterial spectrum, ceftolampil is widely used in clinical practice.